Thursday, October 18, 2012

HAEMOPHILUS INFLUENZAE B INFECTION

Haemophilus influenzae B (HiB) is a bacterial infection that in children causes meningitis or epiglottitis, and in
adults may affect numerous organs. It is spread by close contact and can cause infections in any age group, but is
far more serious in children.
    In children it may cause:-
          - Meningitis, which is an infection of the meninges (covering of the brain) that results in a fever,
          irritability,   lethargy,   seizures   and   coma.   The   onset   of   meningitis   may   be   so   rapid   that   the   child
          may   be   permanently   affected   (eg:   by   deafness,   learning   difficulties   and   other   forms   of   brain
          damage) before any treatment can work.
          -  Epiglottitis, which is a life threatening infection of a piece of cartilage at the back of the throat
          that may swell and block the airways.
    Blood and fluid from the spinal cord can be tested to confirm the diagnosis.
    In   children   potent   antibiotics   are   needed   for   treatment,   and   they   must   be   given   by   injection.   The   swollen
epiglottis (piece of cartilage at the back of the throat) may choke the child before the antibiotics can work, so urgent
hospitalisation and intubation (placing a tube into the throat to permit breathing) is essential.
    Good   recovery   occurs   if   the   infection   is   diagnosed   and   treated   early,   but   permanent   damage   or   death   are
possible in children if treatment delayed.
    A vaccine for infants has been available since 1993 to prevent HiB infections. It is given as three or four doses,
two months apart, starting at two months of age. It is not recommended for use in adults, but is unlikely to cause
problems if given accidentally.        Common: side effects may include redness and soreness at the injection site, while
unusual   effects   may   include   irritability,   tiredness,   sleeplessness,   diarrhoea   and   a   rash.   It   should   be   used   with
caution in fever, acute infection or immune system problems. It must not be inject into a vein.

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